CoQ10, also known as coenzyme Q10, is an important compound that plays many vital roles in the body including energy generation. The body naturally produces CoQ10 however production decreases with age and many degenerative disorders have been associated with low CoQ10 levels.
Hypertrophic cardiomyopathy or a thickening of the muscles in the heart can make it harder for the heart to pump blood and increase the risk of heart failure.
A study on 87 people with hypertrophic cardiomyopathy found that CoQ10 supplementation was able to reduce the average interventricular septal thickness and posterior wall thickness by 22.4% and 23.1% respectively.1 Another study also showed a 24% and 26% reduction in heart wall thickness with CoQ10 supplementation.2
Over a 2 year period CoQ10 supplementation reduced the risk of mortality from heart failure by 43%.4
Researchers have also found oral CoQ10 supplementation can improve left ventricle contractility and improve heart function in congestive heart failure patients.5 A 2016 review of several studies also found CoQ10 supplementation can decrease adverse events in heart failure patients.6
A meta-analysis of 5 studies with a total of 194 patients found that CoQ10 supplementation can significantly improve endothelial function and poor endothelial function has been implicated with developing atherosclerosis.9
CoQ10 has also been shown to reduce platelet size and prevent platelets from sticking together suggesting that supplementation may help prevent blood clots.14
CoQ10 may help improve heart health, heart failure outlook and atherosclerosis.
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